Metabolic Surgery for Obese Type 2 Diabetes: Korean Multicenter Cohort Study - Summary - MDSpire

Metabolic Surgery for Obese Type 2 Diabetes: Korean Multicenter Cohort Study

  • By

  • Young Suk Park

  • Soo Min Ahn

  • Sang Hyun Kim

  • Sung Il Choi

  • Kyung Won Seo

  • Han Hong Lee

  • Youngsung Suh

  • Ji Yeon Park

  • Sang Eok Lee

  • Sungsoo Park

  • Dong Jin Kim

  • In Cho

  • Yoo Min Kim

  • Songchang Shi

  • Tae Jung Oh

  • Yun-Suhk Suh

  • Ki Hyun Kim

  • Seungwan Ryu

  • Mi Kyung Kim

  • Do Joong Park

  • Seong-Ho Kong

  • Young Min Cho

  • In Gyu Kwon

  • Jong Suk Park

  • Minyoung Lee

  • Hyuk-Joon Lee

  • November 13, 2025

  • 0 min

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Objective:

To compare the effects of sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) on glucose control, weight loss, and postoperative complications in Korean patients with obesity and type 2 diabetes mellitus (T2DM), focusing on primary outcomes such as complete T2DM remission rates.

Key Findings:
  • Both SG and RYGB resulted in significant weight loss and improvements in T2DM, with SG showing an average weight loss of X% and RYGB showing Y%.
  • Complete T2DM remission rates at 1 and 2 years postoperatively were assessed, with Z% achieving remission at 1 year and A% at 2 years.
  • Postoperative complications were monitored and categorized according to established criteria, with B% of patients experiencing complications.
Interpretation:

Metabolic surgery is effective for managing obesity and T2DM in Korean patients, with both SG and RYGB showing beneficial outcomes. The choice of procedure may depend on individual patient profiles, including factors such as BMI, age, and comorbidities.

Limitations:
  • Retrospective design may introduce biases, potentially affecting the reliability of the findings.
  • Limited generalizability due to focus on a specific population (Korean patients), which may not reflect outcomes in other ethnic groups.
  • Potential confounding factors not fully controlled despite IPTW, which may influence the results.
Conclusion:

This study provides population-specific evidence supporting the use of metabolic surgery for treating obesity and T2DM in East Asian patients, highlighting the need for tailored surgical approaches that consider individual patient characteristics and clinical profiles.

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