Minimally invasive management of chronic pleural empyema in non-expandable lung: a systematic review of tunneled pleural catheter use as a surgical alternative - Summary - MDSpire

Minimally invasive management of chronic pleural empyema in non-expandable lung: a systematic review of tunneled pleural catheter use as a surgical alternative

  • By

  • Josef Yayan

  • Kurt Rasche

  • Marcus Krüger

  • Christian Biancosino

  • February 26, 2026

  • 0 min

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Objective:

To evaluate the efficacy and safety of tunneled pleural catheters (TPCs) in managing chronic pleural infections in patients with non-expandable lungs, particularly those considered high-risk for surgery.

Key Findings:
  • TPCs showed infection control in the majority of cases, with complete or partial resolution rates reported up to 100% in selected cohorts.
  • The infection rate associated with TPCs was 4.9%, with an infection-related mortality of 0.29%.
  • Post-infection pleurodesis occurred in over 60% of patients.
  • Effective symptom relief and radiological improvement were reported over follow-up periods ranging from weeks to months.
  • Intrapleural fibrinolytics were safely administered via TPCs in selected cases.
Interpretation:

TPCs are a feasible and potentially effective management option for selected patients with chronic pleural infections and non-expandable lungs, facilitating ambulatory care and reducing hospitalization, provided careful patient selection is undertaken.

Limitations:
  • Limited and predominantly observational nature of available evidence.
  • Need for further prospective studies to define the role of TPCs alongside other minimally invasive strategies, such as video-assisted thoracoscopic surgery.
Conclusion:

TPCs should be considered as part of an individualized, multidisciplinary treatment approach for inoperable pleural empyema.

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