Association between serum progesterone levels on the day of embryo transfer and clinical pregnancy outcomes in POSEIDON Group 1 patients - Summary - MDSpire

Association between serum progesterone levels on the day of embryo transfer and clinical pregnancy outcomes in POSEIDON Group 1 patients

  • By

  • Xin Wang

  • Lili Zhuang

  • Luqing Zhang

  • Zhenteng Liu

  • Huishan Zhao

  • Dongmei Zhao

  • Yingqian Peng

  • Hongchu Bao

  • May 28, 2026

  • 0 min

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Objective:

To investigate the relationship between serum progesterone (P) on the day of embryo transfer (ET) and pregnancy outcomes in patients classified as POSEIDON Group 1.

Key Findings:
  • High serum P (≥23.32 ng/mL) was independently associated with a lower clinical pregnancy rate (adjusted OR = 1.454, 95% CI: 1.032-2.048, P = 0.032).
Interpretation:

Limitations:
  • The study is retrospective and may be subject to selection bias.
  • The findings may not be generalizable to other populations outside POSEIDON Group 1.
Conclusion:

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