To compile published data reporting fatal, severe, or long-term complications impacting the biliary system post-COVID-19 infection, specifically focusing on the definition of long-COVID.
Approach:
Key Findings:
23 studies met inclusion criteria after screening 38,148 titles and abstracts, involving a total of X patients.
Hepatobiliary disorders included post-COVID-19 cholangitis, cholecystitis, and hepatitis, affecting Y, Z, and W patients respectively.
COVID-19 has emerged as a significant contributor to both acute and chronic liver injuries.
Interpretation:
The findings indicate a notable prevalence of severe hepatobiliary complications following COVID-19, suggesting the need for ongoing monitoring and management of liver health in recovered patients to improve clinical outcomes.
Limitations:
Exclusion of non-English studies may limit generalizability and introduce language bias.
Potential biases in study selection and data extraction processes.
Conclusion:
The study highlights the importance of recognizing and addressing hepatobiliary disorders as significant long-term complications of COVID-19.
by Ali Aboulwafa, Ahamed Lebbe, Aya Khalil, Nuran Bayraktar, Beshr Mushannen, Sama Ayoub, Shaunak Sarker, Marwan Nour Abdalla, Sa’ad Laws, Ibrahim Mohammed, Lina Yagan, Malik Mushannen, Dalia Zakaria