Comparative analysis of unilateral biportal endoscopy and minimally invasive transforaminal lumbar interbody fusion in treating lumbar spinal brucellosis - Summary - MDSpire

Comparative analysis of unilateral biportal endoscopy and minimally invasive transforaminal lumbar interbody fusion in treating lumbar spinal brucellosis

  • By

  • Cao Rui

  • Yin Ming

  • June 1, 2026

  • 0 min

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Objective:

To compare the clinical efficacy and safety of UBE-TLIF vs. MIS-TLIF in treating lumbar spinal brucellosis.

Key Findings:
  • UBE-TLIF group had significantly shorter operative time, reduced blood loss, and smaller incisions compared to MIS-TLIF (P < 0.05).
  • Postoperative inflammatory markers decreased significantly in both groups with no significant intergroup differences (P > 0.05).
  • UBE-TLIF group had lower VAS scores at 1 and 3 months postoperatively, but differences resolved by 6 months (P > 0.05).
  • Both groups showed significant improvements in ODI and intervertebral disc height postoperatively with no intergroup differences (P > 0.05).
  • Complications included three dural tears (UBE-TLIF) and four nerve root injuries (MIS-TLIF), with comparable complication rates (P > 0.05).
  • Bone fusion rates and MacNab excellent/good rates were similar between groups (P > 0.05).
Interpretation:

Both UBE-TLIF and MIS-TLIF are safe and effective for lumbar spinal brucellosis, with UBE-TLIF providing advantages in terms of minimally invasive benefits.

Limitations:
  • The study is retrospective and may have selection bias.
  • Limited sample size may affect the generalizability of the findings.
Conclusion:

UBE-TLIF offers superior minimally invasive benefits and may be preferred in selected patients.

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