Recurrent meningioma treated with boron neutron capture therapy: a feasibility study with dosimetric and clinical correlates - Summary - MDSpire

Recurrent meningioma treated with boron neutron capture therapy: a feasibility study with dosimetric and clinical correlates

  • By

  • Tien-Li Lan

  • Chun-Fu Lin

  • Yi-Yen Lee

  • Feng-Chi Chang

  • Shih-Chieh Lin

  • Fong-In Chou

  • Jinn-Jer Peir

  • Po-Shen Pan

  • Jen-Kun Chen

  • Lu-Han Lai

  • Hiroki Tanaka

  • Shih-Ming Hsu

  • Yi-Wei Chen

  • July 31, 2025

  • 0 min

Share

Objective:

To evaluate the clinical outcomes and factors influencing treatment response in patients with recurrent meningioma treated with boron neutron capture therapy (BNCT), highlighting its significance in this context.

Key Findings:
  • Include quantitative data on response rates, such as percentages of complete and partial responses.
Interpretation:

BNCT appears to be a feasible treatment option for recurrent meningiomas, offering potential benefits in tumor control with reduced damage to normal brain tissue, which is crucial for patient quality of life.

Limitations:
  • Retrospective design may introduce bias.
  • Small sample size limits generalizability of findings.
  • Lack of long-term follow-up data on survival outcomes.
Conclusion:

BNCT shows promise as a salvage treatment for recurrent meningiomas, warranting further investigation in larger, prospective studies, particularly focusing on long-term outcomes and quality of life.

Original Source(s)

Recurrent meningioma treated with boron neutron capture therapy: a feasibility study with dosimetric and clinical correlates

  • by Tien-Li Lan, Chun-Fu Lin, Yi-Yen Lee, Feng-Chi Chang, Shih-Chieh Lin, Fong-In Chou, Jinn-Jer Peir, Po-Shen Pan, Jen-Kun Chen, Lu-Han Lai, Hiroki Tanaka, Shih-Ming Hsu, Yi-Wei Chen

  • July 31, 2025

Related Content

The Role of Immune Cells and Cytokines in Radiation-Induced Damage: Key Functions and Potential Therapeutic Targets

Induction Immunochemotherapy Followed by Concurrent Chemoradiotherapy Improves Survival in Unresectable Esophageal Cancer: a systematic review, meta-analysis, and network meta-analysis

Impact of alpha-lipoic acid on salivary production in patients receiving radiotherapy for head and neck cancer: a randomized clinical study