Blood pressure variability plays a critical role in determining the prognosis of acute ischemic stroke combined with hypertension - Summary - MDSpire

Blood pressure variability plays a critical role in determining the prognosis of acute ischemic stroke combined with hypertension

  • By

  • Keqiong Yan

  • Lan Ye

  • Mei Wu

  • Jun Yang

  • May 5, 2026

  • 0 min

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Objective:

To investigate the effects of blood pressure variability (BPV) regulation on the prognosis of patients with acute ischemic stroke (AIS) and hypertension, highlighting the significance of BPV in AIS outcomes.

Key Findings:
  • The observation group had higher acute-phase diastolic BPV and worse 90-day mRS and NIHSS scores compared to the control group.
  • Patients in the observation group with improved SBPV showed better 90-day outcomes than those without improvement.
Interpretation:

BPV may serve as a prognostic marker for functional outcomes in AIS, and tailored antihypertensive therapy aimed at reducing BPV is associated with improved patient prognosis, suggesting implications for clinical practice.

Limitations:
  • Small sample size of 75 patients.
  • Single-center study may limit generalizability.
  • Potential biases or confounding factors affecting results.
Conclusion:

Tailored antihypertensive therapy to reduce BPV shows a preliminary association with improved prognosis in AIS patients with hypertension.

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