Evaluating a Tailored Web-Based eHealth Intervention for Symptom Management in Couples Managing Prostate Cancer During the COVID-19 Pandemic: Randomized Clinical Trial - Summary - MDSpire

Evaluating a Tailored Web-Based eHealth Intervention for Symptom Management in Couples Managing Prostate Cancer During the COVID-19 Pandemic: Randomized Clinical Trial

  • By

  • Lixin Song

  • Christine Rini

  • Yuexia Zhang

  • Chunxuan Ma

  • Laurel Northouse

  • Matthew E Nielsen

  • Xianming Tan

  • Ronald C Chen

  • July 10, 2026

  • 0 min

Share

Objective:

To evaluate the efficacy of the Prostate Cancer Education and Resources for Couples (PERC) eHealth intervention on quality of life (QOL) and symptom management in patients with prostate cancer and their partners.

Approach:
  • Study Design: A two-arm, parallel-group, longitudinal randomized controlled trial (RCT) conducted during the COVID-19 pandemic.
  • Participants: Eligible participants included men aged 40-75 years within 4 months post radical prostatectomy or radiation therapy for localized prostate cancer, along with their intimate partners.
  • Procedure: Participants were recruited through the North Carolina Central Cancer Registry Rapid Case Ascertainment service after Institutional Research Board approval.
Key Findings:
  • PERC aimed to enhance QOL by improving positive appraisals, self-efficacy, social support, and symptom management knowledge.
  • The study found that PERC users reported greater improvements in outcomes over time compared to control participants.
Interpretation:

The study addresses the supportive care needs of both patients and partners affected by prostate cancer.

Limitations:
  • The trial's implementation coincided with the COVID-19 pandemic, which may have affected participant engagement and data collection.
Conclusion:

The study evaluates an innovative eHealth intervention tailored for couples affected by prostate cancer, focusing on symptom management and quality of life.

Sources:

Original Source(s)

Related Content