Objective:

To review the clinical features of orbital metastases from breast carcinoma and describe four additional patients.

Approach:

Key Findings:

• Sixty-nine cases of breast carcinoma metastatic to the orbit were reviewed from 63 articles.
• 96% of patients were female, with an average age of 60 years at presentation (range: 31–83).
• 43% of patients had orbital metastasis as the initial manifestation of breast cancer.
• 51% of reported primary tumors were lobular carcinoma, and 43% were ductal carcinoma.
• Common presenting symptoms included diplopia (65%) and decreased or blurry vision (48%).

Interpretation:

Metastatic breast cancer is increasingly characterized by improved survival and prolonged disease control in selected patients.

Limitations:

• The search was limited to a single database, potentially omitting relevant cases indexed elsewhere.
• Documentation of survival time was inconsistent across studies.

Conclusion:

In patients with a history of breast cancer, metastatic disease should be considered in those presenting with orbital pathology.

Attribution Notice

This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.