To examine non-pharmacological interventions targeting insomnia's underlying mechanisms through five physical factor therapies.
Approach:
Key Findings:
Physical factor therapies may serve as promising adjunctive options for selected insomnia phenotypes.
Current evidence for several modalities remains heterogeneous and preliminary.
Advances in portable and home-based technologies support the feasibility of these therapies.
Interpretation:
Future research should focus on larger sham-controlled trials, objective sleep and circadian outcomes, standardized protocols, biomarker-guided stratification, and closed-loop intervention systems.
Limitations:
Evidence remains heterogeneous across different interventions and populations.
Long-term effectiveness, adherence, and cost-effectiveness of these therapies are yet to be established.
Conclusion:
The review highlights the potential of non-pharmacological approaches in treating insomnia while acknowledging the need for further research.