Transrectal versus transperineal prostate fusion biopsy: a pair-matched analysis to evaluate accuracy and complications - Summary - MDSpire

Transrectal versus transperineal prostate fusion biopsy: a pair-matched analysis to evaluate accuracy and complications

  • By

  • Marco Oderda

  • Romain Diamand

  • Rawad Abou Zahr

  • Julien Anract

  • Gregoire Assenmacher

  • Nicolas Barry Delongchamps

  • Alexandre Patrick Bui

  • Daniel Benamran

  • Giorgio Calleris

  • Charles Dariane

  • Mariaconsiglia Ferriero

  • Gaelle Fiard

  • Fayek Taha

  • Alexandre Fourcade

  • Georges Fournier

  • Karsten Guenzel

  • Adam Halinski

  • Giancarlo Marra

  • Guillaume Ploussard

  • Katerina Rysankova

  • Jean-Baptiste Roche

  • Giuseppe Simone

  • Olivier Windisch

  • Paolo Gontero

  • September 25, 2024

  • 0 min

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Objective:

To compare the accuracy and complications of transrectal (TR) and transperineal (TP) prostate biopsies in a large cohort of patients, highlighting the clinical significance of the findings.

Key Findings:
  • Higher detection rate of clinically significant prostate cancer (csPCa) in TP biopsies (50.5%) compared to TR biopsies (36.2%), p < 0.001, indicating a significant advantage for TP biopsies.
  • No significant difference in overall prostate cancer detection rates between TP (68.0%) and TR (70.3%) biopsies, p = 0.39, suggesting comparable effectiveness.
  • TP biopsies showed higher detection rates for csPCa and any PCa in targeted cores compared to TR biopsies, emphasizing the targeted approach's effectiveness.
  • Complication rates were similar between TP and TR approaches, with low incidence of post-biopsy infections, indicating safety in both methods.
Interpretation:

The transperineal approach demonstrates superior detection of clinically significant prostate cancer without increased complications compared to the transrectal approach, which has important implications for clinical practice.

Limitations:
  • Retrospective design may introduce selection bias, which should be considered when interpreting results.
  • Data collected from multiple centers may lead to variability in techniques and outcomes, potentially affecting the generalizability of findings.
Conclusion:

Transperineal biopsies are associated with higher detection rates of clinically significant prostate cancer and comparable complication rates to transrectal biopsies, supporting their use in clinical practice and suggesting a shift in standard biopsy techniques.

Original Source(s)

Transrectal versus transperineal prostate fusion biopsy: a pair-matched analysis to evaluate accuracy and complications

  • by Marco Oderda, Romain Diamand, Rawad Abou Zahr, Julien Anract, Gregoire Assenmacher, Nicolas Barry Delongchamps, Alexandre Patrick Bui, Daniel Benamran, Giorgio Calleris, Charles Dariane, Mariaconsiglia Ferriero, Gaelle Fiard, Fayek Taha, Alexandre Fourcade, Georges Fournier, Karsten Guenzel, Adam Halinski, Giancarlo Marra, Guillaume Ploussard, Katerina Rysankova, Jean-Baptiste Roche, Giuseppe Simone, Olivier Windisch, Paolo Gontero

  • September 25, 2024

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