Trends and Disparities in Mortality Related to Aortic Aneurysm and Aortic Dissection in the United States (1999-2023): An Analysis Using the CDC WONDER Database - Summary - MDSpire

Trends and Disparities in Mortality Related to Aortic Aneurysm and Aortic Dissection in the United States (1999-2023): An Analysis Using the CDC WONDER Database

  • By

  • Lin Lv

  • Xuedi Gao

  • Jia Li

  • Hong lu Wang

  • Hongjia Zhang

  • Sichong Qian

  • Haiyang Li

  • March 3, 2026

  • 0 min

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Objective:

To analyze trends and disparities in mortality related to aortic aneurysm (AA) and aortic dissection (AD) in the U.S. from 1999 to 2023 using the CDC WONDER database, highlighting the significance of these disparities in public health.

Key Findings:
  • AA-related age-adjusted mortality in the U.S. declined from 1999 to 2020, with significant disparities across sex, race/ethnicity, and region, particularly affecting minority groups.
  • AAA mortality in older adults varied by demographic groups, with notable declines in high-income regions, indicating socioeconomic influences.
  • AD mortality showed a decreasing trend from 1999 to 2023, with the highest rates in the elderly population and significant geographical differences, underscoring the need for targeted interventions.
Interpretation:

The study highlights persistent disparities in mortality related to AA and AD, influenced by demographic factors and healthcare access, despite advances in management strategies, suggesting a need for policy changes.

Limitations:
  • Data on urban-rural classification is only available through 2020, limiting the assessment of disparities across the full period and potentially skewing results.
  • The study may not capture all factors influencing mortality trends due to reliance on available data, which could affect the comprehensiveness of the findings.
Conclusion:

The findings underscore the need for targeted interventions and policies to address disparities in AA and AD mortality across different demographic groups, emphasizing the importance of equitable healthcare access.

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