Case Report: Persistent fifth aortic arch with coarctation and fourth aortic arch interruption causing infant heart failure – the prenatal and postnatal echocardiographic course - Summary - MDSpire

Case Report: Persistent fifth aortic arch with coarctation and fourth aortic arch interruption causing infant heart failure – the prenatal and postnatal echocardiographic course

  • By

  • Xiaohong Zhang

  • Guozhen Yuan

  • Kunpeng Li

  • Yangcan Duan

  • Junli Hu

  • Dongchen Fan

  • May 22, 2026

  • 0 min

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Objective:

To provide insights into the prenatal recognition, postnatal management, and clinical decision-making for persistent fifth aortic arch (PFAA) with coarctation and fourth aortic arch interruption, highlighting their significance in improving diagnostic accuracy and patient outcomes.

Key Findings:
  • PFAA with fourth aortic arch interruption is a rare congenital anomaly with significant clinical implications.
  • Prenatal diagnosis is challenging due to the absence of significant hemodynamic changes, necessitating improved training for sonographers.
  • Postnatal closure of the ductus arteriosus can lead to rapid narrowing and heart failure, underscoring the importance of timely intervention.
Interpretation:

The case highlights the difficulties in prenatal diagnosis and the importance of timely surgical intervention for PFAA, suggesting a need for enhanced training and awareness among healthcare providers.

Limitations:
  • Limited awareness among sonographers may contribute to low prenatal detection rates, impacting early diagnosis and treatment.
  • Current literature primarily consists of case reports or small series, indicating a need for larger studies to better understand this anomaly.
Conclusion:

This case provides valuable insights for the diagnosis and management of a rare aortic arch anomaly, suggesting avenues for future research to improve detection and outcomes.

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