Preoperative Conditioning through Prehabilitation in Patients Undergoing Endoscopic Submucosal Dissection: Results from a Randomized Controlled Study - Summary - MDSpire

Preoperative Conditioning through Prehabilitation in Patients Undergoing Endoscopic Submucosal Dissection: Results from a Randomized Controlled Study

  • By

  • Biyun Jiang

  • Shengdi Lu

  • Yiling Yan

  • Ruixin Wang

  • Manrong Xu

  • Lihua Huang

  • Yun Shen

  • November 11, 2025

  • 0 min

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Objective:

To determine whether prehabilitation improves postoperative recovery outcomes in patients undergoing Endoscopic Submucosal Dissection (ESD), addressing a significant knowledge gap.

Key Findings:
  • Prehabilitation may enhance physical functional status and reduce postoperative complications, with specific statistical outcomes to be detailed.
  • Shorter length of hospital stay and improved health-related quality of life were observed.
  • Potential economic benefits through reduced costs associated with complications.
Interpretation:

The study suggests that prehabilitation could be beneficial for patients undergoing ESD, with implications for clinical practice.

Limitations:
  • Single-center study may limit generalizability and introduce biases.
  • Only outcome assessors were blinded, which could introduce bias.
Conclusion:

Prehabilitation shows promise in improving postoperative outcomes for ESD patients, warranting further research in broader settings, particularly multicenter trials.

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