To investigate the risk of hemorrhagic events in brain metastases (BM) from distinct tumor entities and assess the safety of surgical tumor removal, highlighting the significance of these events in surgical outcomes.
Key Findings:
BM from melanoma, kidney carcinoma, and hepatocellular carcinoma have a higher risk of intracerebral hemorrhage, indicating a need for careful monitoring.
Surgical removal of hemorrhagic BM is feasible and safe, suggesting that surgical intervention can be considered in these cases.
Preoperative management of anticoagulation is critical to minimize hemorrhagic complications, emphasizing the need for tailored anticoagulation strategies.
Interpretation:
Patients with specific tumor origins may require tailored surgical approaches due to varying risks of hemorrhagic complications, which could influence surgical planning and postoperative care.
Limitations:
Retrospective design may introduce selection bias, potentially affecting the reliability of findings.
Exclusion of lymphoma and trauma-related cases limits generalizability, suggesting a need for further studies to include these populations.
Conclusion:
Surgical intervention for hemorrhagic BM is safe, but careful consideration of tumor origin and anticoagulation management is essential to optimize patient outcomes.
by Laurèl Rauschenbach, Pia Kolbe, Adrian Engel, Yahya Ahmadipour, Marvin Darkwah Oppong, Alejandro N. Santos, Sied Kebir, Celia Dobersalske, Björn Scheffler, Cornelius Deuschl, Philipp Dammann, Karsten H. Wrede, Ulrich Sure, Ramazan Jabbarli
