Most Salivary Gland Neoplasms Found to Be Benign in Single-Center Study

Analysis of 50 cases shows moderate diagnostic agreement between FNAC and histopathology and identifies pleomorphic adenoma as the most common neoplasm.

By
Olivia Anderson
February 26, 2026
3 min

Conexiant

Objective:

To assess demographic patterns, histopathology, clinical features, anatomic distribution, and short-term outcomes of salivary gland neoplasms.

Approach:

Key Findings:

76% of neoplasms were benign, with pleomorphic adenoma being the most common.
Malignant neoplasms accounted for 24%, primarily mucoepidermoid and adenoid cystic carcinoma.
FNAC showed 100% sensitivity for benign tumors but only 41.7% specificity for malignancy.
Patients ranged in age from 1 to 80 years, with a median age of 45.

Interpretation:

Swelling was the predominant clinical feature, with FNAC being a useful diagnostic tool despite its limitations in specificity, particularly in excluding malignancy.

Limitations:

Small sample size of 50 patients.
Single-center study design.
Short follow-up period of three months, which may affect the assessment of long-term outcomes.