To examine the impact of different forms of endometriosis, specifically ovarian and deep-infiltrating subtypes, on ovarian reserve and the number of retrieved oocytes, and to identify patients who might benefit from fertility preservation through oocyte cryopreservation.
Key Findings:
Endometriosis affects approximately 10% of women of reproductive age and is a significant cause of infertility.
Women with endometriosis have a reduced monthly fecundity rate of 2–5% compared to 15–25% in healthy women.
Diminished ovarian reserve is particularly evident in women with ovarian endometriosis, indicated by significantly reduced AMH levels.
Fertility preservation through oocyte cryopreservation is recommended for women with diminished ovarian reserve due to endometriosis.
Interpretation:
The study highlights the importance of assessing endometriosis subtypes for personalized treatment and fertility preservation strategies, suggesting that tailored approaches may improve outcomes.
Limitations:
The study is retrospective and may be subject to selection bias, potentially affecting the generalizability of the findings.
Lack of globally recognized guidelines for fertility preservation in endometriosis patients limits the applicability of the results.
Conclusion:
A more detailed analysis of endometriosis subtypes is necessary to understand their differential impact on infertility and ovarian reserve, which could inform future clinical guidelines and research.