Sleep-related problems among patients with rheumatoid arthritis in the World Health Organization Eastern Mediterranean region: a systematic review and meta-analysis - Summary - MDSpire
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Sleep-related problems among patients with rheumatoid arthritis in the World Health Organization Eastern Mediterranean region: a systematic review and meta-analysis
To systematically review and meta-analyze the prevalence and correlates of sleep-related problems among adults with rheumatoid arthritis (RA) in WHO Eastern Mediterranean Region countries.
Key Findings:
The pooled prevalence of sleep-related problems among RA patients was 60.9% (95% CI: 56.5%–65.2%).
Subgroup analyses showed pooled prevalence estimates of 58% for insomnia symptoms, 65% for obstructive sleep apnea-related measures, and 61% for poor subjective sleep quality.
Depression was the strongest associated factor with sleep-related problems (OR = 2.65), followed by pain (OR = 2.18), fatigue (OR = 1.91), female gender (OR = 1.67), and older age (OR = 1.42).
Interpretation:
Remove the entire section.
Limitations:
Limited number of contributing countries and studies.
Substantial heterogeneity in sleep constructs and assessment methods.
Publication bias assessments were underpowered.
Conclusion:
Revise to state only the findings without recommendations or implications.
Investigators find that short sleep, insomnia, and night shift work are associated with increased risk of knee and hip osteoarthritis and joint replacement.
