Influenza Vaccine-Averted Illness in Chile, Guyana, and Paraguay During 2013–2018: A Standardized Approach to Assess the Value of Vaccination - Summary - MDSpire

Influenza Vaccine-Averted Illness in Chile, Guyana, and Paraguay During 2013–2018: A Standardized Approach to Assess the Value of Vaccination

  • By

  • Jorge H Jara

  • Sergio Loayza

  • Francisco Nogareda

  • Paula Couto

  • Miguel Angel Descalzo

  • Anna N Chard

  • María Fernanda Olivares Barraza

  • Natalia Vergara Mallegas

  • Rodrigo A Fasce

  • Marta Von Horoch

  • Silvia Battaglia

  • Elena Penayo

  • Chavely Montserrat Dominguez

  • Cynthia Vazquez

  • Rainier Escalada

  • Janice Woolford

  • Fabiana Michel

  • Rafael Chacon

  • Ashley Fowlkes

  • Laura Castro

  • Martha Velandia-Gonzalez

  • Marc Rondy

  • Eduardo Azziz-Baumgartner

  • Stefano Tempia

  • Daniel Salas

  • March 10, 2025

  • 0 min

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Objective:

To estimate vaccine-averted influenza illnesses among young children and older adults in Chile, Guyana, and Paraguay from 2013 to 2018.

Key Findings:
  • In Chile, vaccinating 68% of children aged 6–23 months averted an annual mean of 14,617 nonhospitalized, 9,426 medically attended, and 328 hospitalized influenza illnesses.
  • In Paraguay, vaccinating 28% of children aged 6–23 months averted 1,115 nonhospitalized, 719 medically attended, and 25 hospitalized influenza illnesses.
  • In Chile, vaccinating 59% of older adults averted 83,429 nonhospitalized, 37,079 medically attended, and 1,390 hospitalized influenza illnesses.
  • In Paraguay, vaccinating 36% of older adults averted 3,932 nonhospitalized, 1,748 medically attended, and 66 hospitalized influenza illnesses.
  • A hypothetical campaign in Guyana could have prevented significant numbers of influenza illnesses among children and older adults.
Interpretation:

Influenza vaccination significantly reduced the burden of influenza illnesses and hospitalizations in Chile and Paraguay, indicating the potential benefits of vaccination programs.

Limitations:
  • Data limitations in Guyana due to the absence of a national influenza immunization program.
  • Estimates are based on modeled scenarios which may not capture all real-world complexities.
Conclusion:

Influenza vaccination programs in Chile and Paraguay have averted tens of thousands of illnesses and hospitalizations, highlighting the importance of vaccination in public health strategies.

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