Median Arcuate Ligament Syndrome Masked by Cannabis Hyperemesis Syndrome: A Case Report - Summary - MDSpire
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Median Arcuate Ligament Syndrome Misdiagnosed as Cannabis Hyperemesis Syndrome: A Case Study

  • September 15, 2026

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Objective:

To highlight the diagnostic challenges of median arcuate ligament syndrome (MALS) and its misdiagnosis as cannabis hyperemesis syndrome (CHS).

Approach:
  • Case Report: A 25-year-old woman with recurrent gastrointestinal symptoms was initially diagnosed with CHS. After further evaluation, imaging revealed celiac artery compression due to MALS.
Key Findings:
  • The patient had a history of recurrent vomiting episodes and was initially misdiagnosed with CHS despite negative evaluations.
  • Imaging revealed greater than 70% stenosis of the celiac artery, confirming the diagnosis of MALS.
  • Symptoms of MALS can overlap with more common gastrointestinal disorders, complicating the diagnostic process.
Interpretation:

The case highlights the diagnostic challenges of MALS and the importance of awareness among healthcare providers.

Limitations:
  • The case study is based on a single patient, limiting generalizability.
  • Management options for patients who decline surgery or are pregnant are not well-defined.
Conclusion:

Increased awareness of MALS is necessary to improve diagnostic accuracy. ---

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