To assess the predictive value of NLR, CAR, and their combined use for intracerebral hemorrhage (ICH) in maintenance hemodialysis (MHD) patients, including whether the combined indicator offers incremental discriminative ability beyond either marker alone.
Key Findings:
NLR and CAR levels were significantly higher in the ICH group (P < 0.001).
NLR (OR = 1.24, 95% CI: 1.01–1.54, P = 0.048) and CAR (OR = 2.44, 95% CI: 1.75–3.41, P < 0.001) were independent risk factors for ICH.
ROC analysis showed AUCs of 0.76 for NLR, 0.80 for CAR, and 0.82 for the combined model, with the combined model outperforming single markers (P < 0.05).
Interpretation:
NLR and CAR are effective independent predictors of ICH risk in MHD patients, and their combination enhances predictive accuracy, suggesting a practical tool for early identification in clinical settings.
Limitations:
Retrospective design may introduce bias.
Single-center study limits generalizability.
Potential confounding factors not accounted for may affect results.
Conclusion:
NLR and CAR serve as practical, cost-effective indicators for early identification of high-risk MHD patients for ICH.
