Associations between prevalent unhealthy lifestyles and the gut microbiota: a comprehensive multi-database bibliometric analysis of pathogenic mechanisms and clinical trajectories - Summary - MDSpire
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Associations between prevalent unhealthy lifestyles and the gut microbiota: a comprehensive multi-database bibliometric analysis of pathogenic mechanisms and clinical trajectories
To systematically analyze the research landscape and emerging trends in the field of lifestyle–microbiome interactions, focusing on five predominant unhealthy lifestyles: smoking, alcohol consumption, sleep disorders, sedentary behavior, and high-sugar diets.
Key Findings:
Exponential growth in publication output from 2001 to 2026, indicating increasing research interest.
China and the United States are the leading contributors to the research, highlighting a need for global collaboration.
Core pathophysiological themes identified include inflammation, oxidative stress, obesity, metabolic dysfunction, and microbiome-associated metabolomics, which are critical for public health strategies.
Lifestyle interventions are heavily researched as non-pharmacological strategies for gut microbiota preservation, suggesting potential for practical applications.
Interpretation:
The study provides a comprehensive framework for understanding the interactions between unhealthy lifestyles and gut microbiota, highlighting the importance of inflammation and metabolic dysfunction, which can guide future research and public health initiatives.
Limitations:
The analysis is limited to five specific unhealthy lifestyles, which may not encompass all relevant factors.
Potential publication bias may affect the findings, as studies with positive results are more likely to be published.
Conclusion:
This bibliometric study delineates the structural landscape of research on unhealthy lifestyles and gut microbiota, offering insights for future research and lifestyle-oriented strategies for gastrointestinal health.
