Application of a Cognitive-Structure Framework-Based Scenario-Based Education Programme in Schizophrenia Patients with Delusional Symptoms: A Randomised Controlled Trial - Summary - MDSpire

Application of a Cognitive-Structure Framework-Based Scenario-Based Education Programme in Schizophrenia Patients with Delusional Symptoms: A Randomised Controlled Trial

  • By

  • Hou, Runing

  • Zhou, Yue

  • Su, Kun

  • Zhi, Xiaoyan

  • Yan, Fang

  • Zhang, Yanping

  • Zhang, Lingfang

  • May 7, 2026

  • 0 min

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Objective:

To evaluate the short-term effects of a structured educational program on cognitive function and coping strategies in schizophrenia patients with delusions over a four-week period.

Key Findings:
  • The observation group showed a higher SCSQ score for positive coping and a lower score for negative coping compared to the control group (P < 0.05), with 47 patients completing the training.
  • Total C-CDRS scores and DACOBS scores were significantly better in the observation group (P < 0.05).
  • Neurophysiological indicators showed shortened latencies of N1, N2, and P3, and increased amplitudes of N1 and P3 in the observation group (P < 0.05).
Interpretation:

Scenario-based education can improve coping strategies and reduce delusional symptoms in the short term, with associated changes in neurophysiological indicators, suggesting implications for future research.

Limitations:
  • The study lacks a control group with matched characteristics, which may affect the validity of the findings.
  • There is no long-term follow-up to assess sustained effects, limiting the conclusions.
  • The relationship between neurophysiological changes and clinical cognitive function improvements remains unclear.
Conclusion:

The findings suggest that scenario-based education may have beneficial effects on coping strategies and cognitive distortions in schizophrenia patients with delusions, highlighting the need for further studies to validate these findings.

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