Case report and literature review: the effect of surgical management in intrathoracic pseudomyxoma peritonei - Summary - MDSpire

Case report and literature review: the effect of surgical management in intrathoracic pseudomyxoma peritonei

  • By

  • De-Wang Ren

  • Zhi-Yuan Wang

  • Li-Bin Miao

  • Wei-Qiang Lu

  • Run-Yang Ma

  • Xue-Jun Dou

  • May 18, 2026

  • 0 min

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Objective:

To evaluate clinical outcomes of surgical intervention in patients with intrathoracic pseudomyxoma peritonei (PMP), a rare condition, and review existing literature.

Key Findings:
  • All patients had low-grade PMP with significant pleural effusion and pulmonary lesions.
  • 1- and 3-year survival rates were 100% and 33.3%, respectively, indicating a concerning drop in long-term survival.
  • Cytoreductive surgery combined with HITHOC may alleviate symptoms and improve prognostic outcomes, but further validation is needed.
Interpretation:

Intrathoracic PMP is rare and associated with poor prognosis; however, surgical intervention can provide symptom relief and potentially enhance survival, though the long-term benefits remain uncertain.

Limitations:
  • Small sample size limits generalizability.
  • Retrospective nature may introduce bias.
  • Lack of a control group for comparison.
Conclusion:

Surgical management of intrathoracic PMP can be beneficial, but careful monitoring for complications is essential, and further research is needed to validate these findings.

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