To illustrate the diagnostic and surgical considerations for giant solid pseudopapillary neoplasm (SPN) in an adolescent patient, focusing on the challenges posed by its size and associated complications.
Approach:
Histopathological Evaluation: Histopathology confirmed SPN with negative margins and no nodal metastasis. Immunohistochemistry showed nuclear/cytoplasmic positivity for beta-catenin, loss of E-cadherin, positivity for CD10 and CD56, and partial positivity for lymphoid enhancer-binding factor 1.
Key Findings:
Giant solid pseudopapillary neoplasm can present with acute abdominal pain due to intratumoral degeneration and hemorrhage.
Surgical strategy must balance oncologic safety, bleeding risk, and organ preservation.
Post-splenectomy care should include immunization planning and individualized antibiotic prophylaxis.
Interpretation:
The case illustrates the diagnostic and management challenges associated with giant SPN in adolescents, highlighting the need for careful preoperative planning.
Limitations:
Short-term follow-up limits the assessment of long-term outcomes.
The case report format may not generalize to all patients with SPN, particularly those with different tumor sizes or locations.
Conclusion:
Giant solid pseudopapillary neoplasm is a rare condition that necessitates careful surgical planning and postoperative management tailored to the individual patient's needs.
