To examine the association between recent COVID-19 and mortality after myocardial infarction (MI) and the prognostic importance of COVID-19 vaccination.
Key Findings:
Out of 12,054 MI patients, 337 had recent COVID-19.
Adjusted HR for 30-day mortality in MI patients with recent COVID-19 was 1.64 (95% CI: 1.16–2.31).
Adjusted HR for 180-day mortality was 1.28 (95% CI: 0.92–1.78).
Unvaccinated MI patients with recent COVID-19 had a higher mortality risk (HR: 2.88 for 30-day, 2.09 for 180-day) compared to vaccinated patients.
Interpretation:
Recent COVID-19 is associated with increased short-term mortality after MI, particularly in unvaccinated patients.
Limitations:
Study limited to Danish population, which may affect generalizability.
Potential confounding factors not fully accounted for despite adjustments.
Conclusion:
Recent COVID-19 significantly increases the risk of mortality following MI, especially in individuals without prior vaccination.
