Digital self-management programme for pain, fatigue and faecal incontinence in inflammatory bowel disease: cost-effectiveness analysis of the IBD-BOOST randomised controlled trial - Summary - MDSpire

Digital self-management programme for pain, fatigue and faecal incontinence in inflammatory bowel disease: cost-effectiveness analysis of the IBD-BOOST randomised controlled trial

  • By

  • Chris Roukas

  • Laura Miller

  • Fionn Cléirigh Büttner

  • Thomas Hamborg

  • Vladimir Sergeevich Gordeev

  • Vari Wileman

  • Richard C G Pollok

  • Sonia Saxena

  • Rona Moss-Morris

  • Ailsa Hart

  • James O Lindsay

  • Christine Norton

  • Borislava Mihaylova

  • July 1, 2026

  • 0 min

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Objective:

To assess the cost-effectiveness of the IBD-BOOST digital self-management intervention targeting abdominal pain, fatigue, and faecal incontinence in patients with inflammatory bowel disease (IBD).

Approach:
  • Study Design: A cost-effectiveness analysis was conducted alongside a randomised controlled trial comparing the IBD-BOOST intervention with care as usual over 12 months.
  • Participants: Participants included 391 individuals receiving the IBD-BOOST intervention and 389 receiving care as usual, all experiencing symptoms of fatigue, pain, and/or faecal incontinence.
  • Outcome Measures: Health service use, out-of-pocket expenses, time off work, and health-related quality of life were assessed at baseline, 6-month, and 12-month follow-ups.
Key Findings:
  • The IBD-BOOST intervention resulted in an additional 0.016 QALYs per participant over 12 months (95% CI 0.002 to 0.030).
  • Cost savings of -£304.66 (95% CI -803.51 to 194.18) for healthcare and -£39.48 (95% CI -388.09 to 309.12) for out-of-pocket costs and time off work were observed.
  • Cost-effectiveness was estimated at -£28,633 (95% CI -51,555 to 18,764) per QALY gained from a health services perspective and -£33,568 (95% CI -64,421 to 26,198) from a societal perspective.
Interpretation:

The IBD-BOOST intervention is highly likely to be cost-effective for managing pain, fatigue, and faecal incontinence in people with IBD.

Limitations:
  • The primary trial outcomes did not show statistically significant improvements.
  • The analysis focused on secondary health economic outcomes.
Conclusion:

The IBD-BOOST intervention is likely to improve quality of life while being cost-effective for patients with IBD experiencing specific symptoms.

Sources:

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