Boosting hemianopia recovery: the power of interareal cross-frequency brain stimulation - Summary - MDSpire

Boosting hemianopia recovery: the power of interareal cross-frequency brain stimulation

  • By

  • Estelle Raffin

  • Michele Bevilacqua

  • Fabienne Windel

  • Pauline Menoud

  • Roberto F Salamanca-Giron

  • Sarah Feroldi

  • Sarah B Zandvliet

  • Nicola Ramdass

  • Laurijn Draaisma

  • Patrik Vuilleumier

  • Adrian G Guggisberg

  • Christophe Bonvin

  • Lisa Fleury

  • Krystel R Huxlin

  • Elena Beanato

  • Friedhelm C Hummel

  • November 17, 2025

  • 0 min

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Objective:

To investigate the efficacy of a novel cross-frequency brain stimulation protocol in enhancing visual recovery in stroke patients, emphasizing its innovative approach.

Key Findings:
  • cf-tACS significantly improved motion discrimination performance in stroke patients, with p-values indicating statistical significance.
  • Visual field borders shifted, indicating localized enlargement of isopters.
  • Behavioral improvements correlated with residual structural fibers and perilesional primary visual cortex activity.
Interpretation:

The cf-tACS approach effectively boosts perceptual training outcomes, enhancing visual motion processing and reducing visual impairments in stroke patients, with potential implications for clinical rehabilitation.

Limitations:
  • Small sample size of 16 stroke patients may limit generalizability and increase the risk of Type I error.
  • Short duration of the intervention may not reflect long-term effects, necessitating further studies.
Conclusion:

cf-tACS represents a promising, innovative method to enhance visual recovery in stroke patients, potentially improving quality of life, but further research is needed to validate these findings.

Original Source(s)

Boosting hemianopia recovery: the power of interareal cross-frequency brain stimulation

  • by Estelle Raffin, Michele Bevilacqua, Fabienne Windel, Pauline Menoud, Roberto F Salamanca-Giron, Sarah Feroldi, Sarah B Zandvliet, Nicola Ramdass, Laurijn Draaisma, Patrik Vuilleumier, Adrian G Guggisberg, Christophe Bonvin, Lisa Fleury, Krystel R Huxlin, Elena Beanato, Friedhelm C Hummel

  • November 17, 2025

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