Gastric metastasis from hormone receptor–positive breast cancer ten years after radical mastectomy: a case report and literature review - Summary - MDSpire

Gastric metastasis from hormone receptor–positive breast cancer ten years after radical mastectomy: a case report and literature review

  • By

  • Qiang Zhan

  • Gao Wang

  • Hongxia Wan

  • May 15, 2026

  • 0 min

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Objective:

To report a case of gastric metastasis from hormone receptor-positive breast cancer occurring 10 years after radical mastectomy, highlighting the rarity of this phenomenon and reviewing existing literature.

Key Findings:
  • Gastric metastasis from breast cancer is rare, accounting for 0.3-2% of cases.
  • The patient presented with symptoms mimicking primary gastric cancer, complicating diagnosis.
  • Endoscopic biopsy and immunohistochemistry were crucial for accurate diagnosis, highlighting their importance in clinical practice.
Interpretation:

Late gastrointestinal metastasis should be considered in long-term breast cancer survivors, and multidisciplinary evaluation is essential for diagnosis and treatment planning, with implications for clinical practice.

Limitations:
  • Lack of complete original clinical and pathological records from the initial breast cancer treatment.
  • Limited follow-up information after treatment due to patient decline, impacting the findings.
Conclusion:

This case underscores the importance of recognizing potential late metastasis in breast cancer survivors and the effectiveness of targeted therapies in managing such cases, emphasizing the need for early detection.

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