Objective:

To evaluate the efficacy of Combined endurance and resistance exercise training in patients with heart failure (HF) and provide an evidence-based foundation for clinical management.

Approach:

Key Findings:

• Nine studies met the inclusion criteria.
• The intervention group showed significantly greater improvement in peak oxygen consumption (MD = 4.36, 95% CI: 1.68–7.04, P = 0.001).
• Quality of life improved in the intervention group (MD = -9.32, 95% CI: -16.92 to -1.71, P = 0.02).
• Performance on the six-minute walk test was significantly better in the intervention group (MD = 53.76, 95% CI: 38.81–68.70, P < 0.0001).
• No statistically significant differences were observed regarding sleep parameters or depression levels.

Interpretation:

Combined endurance and resistance exercise training is beneficial for improving clinical outcomes in HF patients.

Limitations:

• Significant heterogeneity in sample size and intervention protocols among studies.
• Most studies focused on single exercise modalities.

Conclusion:

The findings suggest that combined endurance and resistance exercise training may improve clinical outcomes in HF patients.

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