The association of anxiety, depression, sleep quality and intradialytic hypotension in hemodialysis patients: a cross-sectional study - Summary - MDSpire

The association of anxiety, depression, sleep quality and intradialytic hypotension in hemodialysis patients: a cross-sectional study

  • By

  • Xiaomei Jiang

  • Panpan Chen

  • Siyan Deng

  • Yujuan Yang

  • Yixiu Liu

  • Shuixiang Wu

  • Qinjuan Xu

  • Huagang Hu

  • Xiaowen Zhu

  • June 5, 2026

  • 0 min

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Objective:

To examine the prevalence of intradialytic hypotension (IDH), anxiety, depression, and poor sleep in maintenance hemodialysis (MHD) patients, and to explore the association of IDH with these symptoms.

Key Findings:
  • IDH incidence was 11.7% across 16,812 dialysis sessions.
  • 26.3% of patients experienced frequent IDH (≥4 episodes).
  • Anxiety was present in 30.4% of patients, depression in 44.3%, and poor sleep in 39.9%.
  • Frequent IDH was significantly associated with higher anxiety, depression, and poor sleep quality scores (P< 0.05).
Interpretation:

Frequent IDH correlates with greater symptom burden of anxiety, depression, and poor sleep quality in MHD patients.

Limitations:
  • Cross-sectional design limits causal inference.
  • Data collected from a single geographic area may affect generalizability.
  • Self-reported measures may introduce bias.
Conclusion:

Findings suggest the need for integrating hemodynamic monitoring with psychological and sleep assessments in MHD care.

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