Wearable-derived cardiovascular fitness age and its lifestyle correlates in 442 adults - Summary - MDSpire

Wearable-derived cardiovascular fitness age and its lifestyle correlates in 442 adults

  • By

  • Aditi Shanmugam

  • Kanika Gupta

  • Nihav Dhawale

  • Vatsal Singhal

  • Mohit Kumar

  • Bhuvan Srinivasan

  • Vinayak Narasimhan

  • July 7, 2026

  • 0 min

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Objective:

To characterize Cardio Age derived from wearable devices and its association with independent lifestyle factors.

Approach:
  • Study Design: Retrospective observational cohort study of 442 Ultrahuman Ring users over 12 months.
  • Data Analysis: Used Spearman rank correlations, extreme-group comparisons, and longitudinal trajectories.
Key Findings:
  • Mean Cardio Age gap was -1.84 ± 2.97 years; 82.6% of participants had younger estimated cardiovascular ages.
  • Significant associations with independent lifestyle metrics: sleep efficiency (r = -0.194, p < 0.001), REM sleep (r = -0.203, p < 0.001), sleep duration (r = -0.200, p < 0.001), and daily steps (r = -0.145, p = 0.003).
  • Underweight participants had a mean CA gap of -3.73 years compared to -0.52 for obese participants.
  • Users with the youngest cardiovascular ages had longer sleep duration and higher sleep efficiency.
Interpretation:

Cardio Age reflects physiological and behavioral variations beyond algorithmic inputs, indicating its potential as a continuous cardiovascular fitness indicator.

Limitations:
  • Study is observational and may not establish causation.
  • Potential algorithmic circularity due to Cardio Age being derived from VO2 max.
Conclusion:

Cardio Age may serve as a practical tool for monitoring cardiovascular fitness, capturing real physiological changes over time.

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