The influence of age in the progression from pre-myopia to myopia onset: a 1 year retrospective analysis - Summary - MDSpire

The influence of age in the progression from pre-myopia to myopia onset: a 1 year retrospective analysis

  • By

  • Shuang Wang

  • Keke Huang

  • Xingyu He

  • Zhanfeng Wang

  • July 7, 2026

  • 0 min

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Objective:

To investigate the effect of age on annual axial elongation during the transition from pre-myopia to myopia in children.

Approach:
  • Study Design: A retrospective study involving 53 children aged 6–10 years who progressed from pre-myopia to myopia within 1 year.
  • Data Collection: Data included age, sex, spherical equivalent refraction, and axial length, with follow-ups every 6 months.
  • Statistical Analysis: Annual axial elongation was analyzed using ANCOVA, with age as a fixed factor and baseline ocular biometrics as covariates.
Key Findings:
  • Annual axial elongation decreased with increasing age: 0.76 mm (6y), 0.64 mm (7y), 0.54 mm (8y), 0.37 mm (9y), and 0.38 mm (10y).
  • Significant main effect of age on axial elongation was found (p = 0.019).
  • Children aged 6 and 7 years had significantly greater axial elongation than those aged 9 years (p < 0.01).
  • Each additional year of age was associated with a 0.093 mm decrease in annual axial elongation (p = 0.002).
Interpretation:

Limitations:
  • The study is retrospective and may not account for all environmental and familial risk factors.
  • Data was collected from a single hospital, which may limit generalizability.
Conclusion:

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