Optimizing healthcare resources in pyogenic liver abscess: a dual-threshold HDL-CRP model for predicting hospitalization duration across multi-cohorts - Summary - MDSpire
Advertisement
Optimizing healthcare resources in pyogenic liver abscess: a dual-threshold HDL-CRP model for predicting hospitalization duration across multi-cohorts
To determine if admission high-density lipoprotein cholesterol (HDL-C) predicts length of stay (LOS) in patients with pyogenic liver abscess (PLA) and to develop a dual-threshold model incorporating CRP.
Key Findings:
Lower HDL-C levels were independently associated with longer LOS.
A nomogram combining HDL-C, abscess size, and sepsis showed good predictive performance.
The dual-threshold (HDL-C 1.0 mg/dL) identified a subgroup with higher odds of prolonged stay.
Interpretation:
Admission HDL-C, particularly when assessed alongside CRP, can effectively identify PLA patients at risk for extended hospitalization, suggesting the need for closer monitoring and proactive management.
Limitations:
The study was conducted at a single tertiary center, which may limit generalizability.
The retrospective validation cohort may introduce biases inherent to observational data.
Conclusion:
The findings support the use of admission HDL-C and CRP as practical tools for early risk stratification in PLA patients, warranting further prospective implementation studies.
