Granulomatosis with polyangiitis initially presenting as secretory otitis media: a case report - Summary - MDSpire

Granulomatosis with polyangiitis initially presenting as secretory otitis media: a case report

  • By

  • Zhang, Zihan

  • CHEN, YIXI

  • Zeng, Yinping

  • Tang, Zhendong

  • Gu, Jiawei

  • Ma, Wenbo

  • Duan, Tingting

  • Zhou, Xuejun

  • June 8, 2026

  • 0 min

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Objective:

To report a case of granulomatosis with polyangiitis (GPA) initially presenting as secretory otitis media, highlighting the challenges in diagnosis and the importance of early recognition.

Approach:
    Key Findings:
    • GPA can present with otological symptoms, which may lead to misdiagnosis and delayed treatment.
    • The patient exhibited facial paralysis and profound hearing loss without other systemic symptoms initially.
    • Early diagnosis and treatment are crucial to prevent complications.
    Interpretation:

    The case illustrates the atypical presentation of GPA and the necessity for otolaryngologists to consider systemic diseases in patients with refractory otological symptoms, particularly when conventional treatments fail.

    Limitations:
    • The case is based on a single patient, limiting generalizability.
    • The initial misdiagnosis may have contributed to the delay in appropriate treatment, highlighting the need for awareness of GPA.
    Conclusion:

    Maintaining a high index of suspicion for GPA in patients with persistent otological symptoms is essential for timely intervention and to prevent irreversible complications.

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