To evaluate the efficacy of the dual-layer micromesh Roadsaver stent compared to first-generation carotid stents in patients undergoing transfemoral carotid artery stenting.
Approach:
Systematic Review and Meta-Analysis: Conducted a systematic review and meta-analysis following Cochrane recommendations, focusing on 30-day stroke and death rates, and 12-month in-stent restenosis rates.
Literature Search: Searched electronic databases (PubMed, Embase, Medline) for European studies published in English from January 1, 2014, to December 31, 2024.
Key Findings:
The Roadsaver stent features a dual-layer micromesh design that enhances plaque coverage and minimizes embolic potential.
The stent's low-profile design allows for better navigability in complex vascular anatomies.
Meta-analysis results indicated differences in clinical outcomes between the Roadsaver and first-generation stents.
Interpretation:
Limitations:
The review was limited to studies published in English and focused on European populations, which may affect generalizability.
Potential publication bias and variations in study designs could influence the meta-analysis results.
