Case Study: An Emerging Etiology for ST-Segment Elevation in Lead aVR - Summary - MDSpire

Case Study: An Emerging Etiology for ST-Segment Elevation in Lead aVR

  • By

  • Wei Li

  • Yang Liu

  • Pan Feng

  • Chaoji Huangfu

  • Dayong Du

  • April 29, 2026

  • 0 min

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Objective:

To identify alternative causes of ST-segment elevation in lead aVR in post-CABG patients, particularly focusing on extracoronary vascular lesions and their clinical implications.

Key Findings:
  • Left subclavian artery stenosis can cause ST elevation in lead aVR by limiting inflow to the LIMA graft, which is significant for post-CABG management.
  • Coronary-subclavian steal syndrome is an under-recognized complication in post-CABG patients, necessitating awareness among clinicians.
  • A significant inter-arm systolic blood pressure difference can indicate proximal inflow disease, serving as a diagnostic clue.
Interpretation:

This case highlights the need for thorough evaluation of extracoronary vascular lesions in post-CABG patients experiencing recurrent ischemia, even with patent grafts, emphasizing the importance of comprehensive diagnostic approaches.

Limitations:
  • The study is based on a single case, limiting generalizability and necessitating further research.
  • Quantitative flow data was not measured during the intervention, which could provide additional insights.
Conclusion:

Recognition and treatment of left subclavian artery stenosis can effectively resolve ischemic symptoms and ECG changes in post-CABG patients, underscoring the importance of evaluating extracoronary lesions.

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