To examine 20-year trends in cerebral palsy (CP) birth prevalence in Sweden and changes in functional severity classified by GMFCS and MACS.
Approach:
Design and data: Retrospective population-based cohort study using the Swedish Cerebral Palsy Follow-Up Program (CPUP) registry and live-birth data from Statistics Sweden.
Population: Included people born in Sweden from 2000 through 2019 and registered in CPUP; birth totals were adjusted to match regions contributing registry data in each year.
Measures: The primary outcome was annual CP birth prevalence per 1,000 live births. Functional severity was assessed using GMFCS and MACS classifications recorded nearest age 5, from assessments between ages 4 and 10.
Interpretation:
The provided context describes the study rationale and methods but does not report results, so trends in prevalence or functional severity cannot be summarized.
Limitations:
The supplied context ends before the results and discussion.
Registry data were available from 17 of Sweden’s 21 healthcare regions, with reporting beginning in different years across some regions.
Investigators linked distinct odor patterns to life stage, sex, and skin microbes, while limited longitudinal evidence leaves their clinical utility uncertain.
