To characterize diagnostic stability, transitions from non-SMI to SMI, and sex- and age-related predictors in Chinese adolescent inpatients.
Key Findings:
81% of schizophrenia spectrum disorders and 74% of bipolar disorders remained unchanged over follow-up.
39.2% of patients experienced at least one diagnostic change, primarily within non-SMI categories.
Depressive disorders were the most frequent antecedent of bipolar disorder conversion.
Males had approximately twice the risk of SMI conversion compared to females after adjusting for age.
Interpretation:
Adolescent psychiatric diagnoses show substantial longitudinal evolution, with stable SMI once established but significant progression from non-SMI to SMI, particularly in older males with severe or atypical presentations.
Limitations:
Exploratory nature of subgroup analyses due to small sample sizes.
Findings may not be generalizable beyond the studied population.
Conclusion:
The study supports the need for longitudinal, developmentally informed monitoring of adolescents at high risk for SMI, especially during the 4-to-8-year window post-first admission.
Swedish study finds two-way associations between premenstrual disorders and psychiatric conditions, with strongest links involving depression, anxiety, attention-deficit/hyperactivity disorder, bipolar disorder, and personality disorders.
