Diabetic Retinal Disease Rates Narrow by Diabetes Type - Summary - MDSpire
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Diabetic Retinal Disease Rates Narrow by Diabetes Type
US claims data showed rising prevalence of diabetic retinal disease in type 1 and type 2 diabetes, while incidence declined in type 1 diabetes and moved closer to type 2 rates by 2022.
To analyze the prevalence and incidence of diabetic retinal disease (DRD) among patients with type 1 and type 2 diabetes from 2016 to 2022.
Key Findings:
DRD prevalence increased from 25% to 34% in type 1 diabetes and from 11% to 21% in type 2 diabetes between 2016 and 2021.
Overall DRD incidence in type 1 diabetes declined from 55.1 to 39.2 cases per 1,000 person-years, while type 2 diabetes incidence ranged from 31.6 to 38.5 cases.
The incidence rate ratio for type 1 vs type 2 diabetes decreased from 2.00 in 2016 to 1.43 in 2022.
VTDR, DME, and PDR incidence remained higher in type 1 diabetes throughout the study period.
Interpretation:
Despite a narrowing incidence gap for overall DRD, patients with type 1 diabetes still face a greater burden of DRD compared to those with type 2 diabetes.
Limitations:
Study relied on administrative claims and diagnostic coding without chart-level validation.
Data set was not nationally representative and excluded uninsured patients.
Lacked clinical details such as diabetes duration and glycemic control.
COVID-19 pandemic may have influenced healthcare utilization and results.
Conclusion:
Patients with type 1 diabetes have a higher burden of diabetic retinal disease than those with type 2 diabetes, although the incidence gap for overall disease has narrowed over time.
Mendelian randomization analyses linked higher birthweight with greater mid-childhood height but the connection could reflect genetic factors related to skeletal growth.
