Pandemic-Related Disruptions and Hepatocellular Carcinoma Surveillance in Safety-Net Settings - Summary - MDSpire

Pandemic-Related Disruptions and Hepatocellular Carcinoma Surveillance in Safety-Net Settings

  • By

  • Robert J. Wong

  • Patricia Jones

  • Bolin Niu

  • Paulo Pinheiro

  • Mae Thamer

  • Onkar Kshirsagar

  • Yi Zhang

  • Ronnie Fass

  • Daniela Prieto-Bello

  • Lisa Quirk

  • George Therapondos

  • Amit G. Singal

  • Mandana Khalili

  • May 22, 2026

  • 0 min

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Objective:

To understand whether HCC surveillance has rebounded from the initial COVID-19–related disruptions in care among safety-net health populations, specifically those in California, Florida, Louisiana, Ohio, and Texas.

Key Findings:
  • A total of 6940 patients with cirrhosis were identified, with a median age of 58 years, highlighting the demographic profile of the affected population.
  • HCC surveillance utilization was previously reported at 24.0% among patients with cirrhosis, indicating a significant gap in care.
  • A prior study showed a 44% decline in HCC surveillance rates among veterans with cirrhosis during the early pandemic, underscoring the pandemic's impact.
Interpretation:

The study aims to assess the recovery of HCC surveillance rates in safety-net populations post-pandemic.

Limitations:
  • The study may not fully capture the impact of ongoing healthcare disruptions beyond the initial pandemic phase, which could lead to an underestimation of the long-term effects.
  • Exclusion of patients with a history of HCC at the time of cirrhosis identification may limit generalizability, particularly in understanding the full spectrum of HCC surveillance needs.
Conclusion:

The study seeks to provide insights into the effects of the COVID-19 pandemic on HCC surveillance in vulnerable populations, emphasizing the need for targeted interventions to improve care.

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