Relapsing allergic bronchopulmonary aspergillosis as a trigger for Kounis syndrome: a case report
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By
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Haolei Wei
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Liyan Wu
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Bin Ni
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Jingyu Zhang
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Mengxia Xu
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Liang Guo
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Yanping Mao
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June 9, 2026
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Objective:
To report a case of Kounis syndrome potentially triggered by allergic bronchopulmonary aspergillosis (ABPA).
Key Findings:
- The patient had marked eosinophilia and elevated total IgE during an ABPA relapse.
- Cardiac troponin I and B-type natriuretic peptide levels indicated myocardial injury.
- Coronary angiography revealed nonobstructive coronary arteries, supporting the diagnosis of Kounis syndrome.
Interpretation:
This case describes a patient with Kounis syndrome diagnosed during an ABPA relapse.
Limitations:
- The case is based on a single patient, limiting generalizability.
- No standardized clinical guidelines for the management of Kounis syndrome exist.
Conclusion:
The findings highlight the presentation of Kounis syndrome in patients with severe allergic airway disease.
