To investigate the clinical characteristics, diagnostic approach, perioperative management, and key considerations in surgical decision-making for functional bladder paraganglioma.
Approach:
Retrospective Analysis: Conducted a retrospective analysis of clinical data from a patient with pathologically confirmed bladder paraganglioma and discussed findings in the context of relevant literature.
Key Findings:
The patient was a 50-year-old man who presented with frequent urination, urinary urgency, dysuria, and paroxysmal hypertension during urination.
Diagnostic transurethral resection confirmed paraganglioma, with elevated plasma norepinephrine and methoxy norepinephrine levels.
Postoperative pathology indicated bladder paraganglioma invading the full thickness of the bladder detrusor muscle with no lymph node metastasis.
Multidisciplinary perioperative management and individualized surgical resection were emphasized as key to improving prognosis.
Interpretation:
Urination-related paroxysmal hypertension is a notable sign of functional bladder paraganglioma. Preoperative catecholamine metabolite testing and pelvic MRI are important for diagnosis.
Limitations:
The study is based on a single case, limiting generalizability.
The retrospective nature may introduce bias in data collection and interpretation.
Conclusion:
Lifelong follow-up is mandatory for all patients with bladder paraganglioma.
