Femtosecond laser-assisted LASIK in the SMILE era: a mini review of patient-centered procedure selection - Summary - MDSpire

Evaluating Femtosecond Laser-Assisted LASIK in the Context of SMILE: A Brief Review of Patient-Focused Procedure Choices

  • By

  • Zitong Yu

  • Tong Qin

  • July 20, 2026

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Objective:

To propose a phenotype-centered expert framework for evaluating the role of FS-LASIK in comparison to other refractive procedures, particularly SMILE.

Approach:
  • Literature Review: Synthesis of evidence across various domains including visual outcomes, optical quality, ocular surface effects, corneal nerves, biomechanics, and patient preferences.
Key Findings:
  • FS-LASIK remains relevant for eyes that are structurally safe and likely to benefit from customized excimer ablation.
  • Procedure choice should consider not only visual acuity but also optical quality, ocular surface vulnerability, and patient preferences.
  • FS-LASIK offers advantages in customized ablation techniques that can address specific optical aberrations.
Interpretation:

The review presents a phenotype-centered approach to selecting refractive surgery procedures.

Limitations:
  • The review does not provide formal graded guidelines for procedure selection, and the narrative synthesis may not encompass all recent developments in refractive surgery.
Conclusion:

FS-LASIK can be a suitable option in specific clinical scenarios, particularly for eyes that are structurally safe and likely to benefit from customized optical solutions.

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