Objective:

To evaluate the incidence of disease-specific mortality (DSM) in patients with high-grade dysplasia (HGD) or low-risk T1 esophageal adenocarcinoma (EAC) undergoing endoscopic eradication treatment (EET).

Approach:

Key Findings:

• The study aims to evaluate the incidence of disease-specific mortality in patients with BE-related neoplasia treated with EET.
• Recurrence rates of EAC after 10 years are reported as 4.1%.

Interpretation:

Limitations:

• The study is limited to a single tertiary referral center, which may affect generalizability.
• A small proportion of patients (<10%) did not consent to the prospective study, relying on retrospective data for those cases.

Conclusion:

The study presents data on disease-specific mortality and outcomes in patients with early-stage neoplasia related to Barrett's esophagus after endoscopic intervention.

Sources:

• Study Registry
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