Objective:

To report a case of a 22-year-old man who developed neuropsychiatric symptoms after chronic use of tiletamine-containing e-cigarettes.

Approach:

Key Findings:

• The patient experienced progressive neuropsychiatric symptoms after chronic use of tiletamine-containing e-cigarettes.
• Symptoms included gait instability, dysarthria, hand tremor, emotional instability, and marked craving.
• Brain MRI and electromyography showed no structural abnormalities, while electroencephalography suggested functional brain involvement.
• Symptoms improved after discontinuation of tiletamine use and treatment.

Interpretation:

Chronic tiletamine abuse via e-cigarettes may lead to persistent neuropsychiatric dysfunction and dependence-related features.

Limitations:

• The actual chemical composition of the e-cigarette cartridges was not analytically confirmed.
• No toxicological screening for tiletamine or other substances was performed at presentation.

Conclusion:

This case suggests that chronic use of tiletamine-containing e-cigarettes can result in significant and lasting neuropsychiatric impairment.

Attribution Notice

This content is an AI-generated, fully rewritten summary based on a published scholarly article. It does not reproduce the original text and is not a substitute for the original publication. Readers are encouraged to consult the source for full context, data, and methodology.