Preoperative Cobb angle-guided surgical decision-making between percutaneous kyphoplasty and short-segment fixation with vertebroplasty in stage III Kümmell disease without neurological deficits: a two-center retrospective study - Summary - MDSpire

Preoperative Cobb angle-guided surgical decision-making between percutaneous kyphoplasty and short-segment fixation with vertebroplasty in stage III Kümmell disease without neurological deficits: a two-center retrospective study

  • By

  • Jun Hu

  • Long Tang

  • Yi Liu

  • Hong Yang

  • Yu Qiao

  • Xin Wang

  • July 17, 2026

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Objective:

To compare clinical and radiographic outcomes of percutaneous kyphoplasty (PKP) and short-segment fixation with vertebroplasty (SSF+VP) in patients with stage III Kümmell disease (KD) without neurological deficits, and to evaluate the preoperative local Cobb angle for guiding surgical decision-making.

Approach:
  • Study Design: A two-center retrospective study involving 117 patients who underwent surgery between January 2019 and December 2024.
  • Patient Groups: 71 patients underwent PKP and 46 underwent SSF+VP.
  • Data Collected: Perioperative parameters, VAS, ODI, local Cobb angle, Cobb angle loss, cement distribution, and cement leakage were compared.
  • Analysis Methods: ROC analysis assessed the predictive value of the preoperative Cobb angle for residual mild pain after PKP.
Key Findings:
  • PKP resulted in shorter operative time, less blood loss, smaller cement volume, and greater early improvement in VAS and ODI compared to SSF+VP.
  • SSF+VP showed lower VAS at final follow-up and better maintenance of Cobb angle correction.
  • Cobb angle loss in the PKP group correlated positively with final VAS.
  • The optimal preoperative Cobb angle cut-off for predicting residual pain after PKP was 25.95°.
Interpretation:

Both PKP and SSF+VP improved pain and function in stage III KD without neurological deficits, with PKP allowing faster early recovery and SSF+VP providing better long-term outcomes in severe kyphosis cases.

Limitations:
  • The study is retrospective and may have inherent biases related to patient selection and data collection.
  • The sample size may limit the generalizability of the findings.
Conclusion:

Preoperative Cobb angle-based stratification may assist in guiding individualized surgical selection for patients with stage III KD.

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