To evaluate the efficacy and safety of low-power ultrasound biomodulation (TULIP) for intraocular pressure (IOP) reduction in glaucoma patients.
Approach:
Key Findings:
Mean IOP reduction of approximately 25.8% compared to control.
No evidence of thermal injury or structural tissue disruption was observed.
Stability of retinal nerve fiber layer thickness and no progression of visual field indices were noted.
Bilateral IOP reduction observed in the untreated contralateral eye.
Interpretation:
The findings suggest that TULIP may provide a safe and effective noninvasive option for IOP reduction in glaucoma patients, with potential neuro-autonomic mechanisms influencing outcomes.
Limitations:
Small sample size (n=15) and limited follow-up duration.
Need for larger studies to confirm findings and assess long-term safety and durability.
Conclusion:
TULIP represents a promising approach to IOP management in glaucoma, emphasizing noninvasive treatment and potential for repeated interventions without tissue damage.
