A structured music-based intervention for motor rehabilitation and exploratory cognitive and quality-of-life outcomes after stroke: a study protocol for a randomized waitlist-controlled intervention study - Summary - MDSpire

A structured music-based intervention for motor rehabilitation and exploratory cognitive and quality-of-life outcomes after stroke: a study protocol for a randomized waitlist-controlled intervention study

  • By

  • Aída Estévez

  • Miguel Ángel Pérez Nieto

  • Laura Herrero

  • July 1, 2026

  • 0 min

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Objective:

To evaluate the effects of a structured music-based intervention on motor function after stroke, with exploratory outcomes including executive functioning and stroke-specific quality of life.

Approach:
  • Study Design: A randomized waitlist-controlled intervention study involving adults aged 18–70 who have experienced a stroke at least 3 months prior.
  • Intervention: Participants will be divided into an experimental group receiving standard rehabilitation care plus a structured music-based intervention and a waitlist group receiving only standard care initially.
  • Assessment Timeline: Assessments will occur at baseline, post-intervention (week 5), after group crossover (week 10), and at a 3-month follow-up.
  • Outcome Measures: Primary outcome is motor function; secondary outcomes include upper-limb motor function, executive functioning, and stroke-specific quality of life.
  • Statistical Analysis: Analyses will follow the intention-to-treat principle using linear mixed-effects models.
Key Findings:
  • Structured music-based interventions may enhance motor coordination and motivation.
  • Potential benefits include improvements in emotional regulation, social interaction, and perceived quality of life.
Interpretation:

The study aims to provide preliminary evidence on the feasibility and potential effects of integrating music-based interventions into post-stroke rehabilitation.

Limitations:
  • The study is limited to a single outpatient neurological rehabilitation center initially.
  • Findings may not be generalizable beyond the studied population.
Conclusion:

This study seeks to fill a gap in existing research by evaluating a comprehensive music-based intervention that integrates motor rehabilitation with cognitive and psychosocial components.

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