Objective:

To summarize the applications and future perspectives of jump assessment in multiple sclerosis (MS) for detecting early neuromuscular deficits and guiding individualized neurorehabilitation strategies.

Key Findings:

• Traditional clinical tools like the EDSS lack sensitivity for detecting subtle neuromuscular dysfunction in pwMS, highlighting the need for more effective assessment methods.
• Jump assessments provide objective markers of strength, coordination, and balance, enabling early detection of motor deficits and informing rehabilitation strategies.
• High-challenge tests are necessary to reveal neuromuscular deficits in pwMS with low levels of disability, suggesting a need for more comprehensive assessment approaches.

Interpretation:

Jump assessments represent a promising method for identifying early neuromuscular impairments in pwMS, which can significantly guide individualized neurorehabilitation strategies and improve patient outcomes.

Limitations:

• Current knowledge on jump assessment in MS is limited, with few studies exploring its full potential.
• Existing procedures may not fully capture the complexity of neuromuscular function, particularly in early-stage MS.

Conclusion:

Jump assessment could enhance long-term care and monitoring of pwMS by detecting subtle neuromuscular deficits early, ultimately improving rehabilitation outcomes.